Conquinamine

Title: Conquinamine
CAS Registry Number: 464-86-8
CAS Name: (3aR,8aS)-8a-[(1S,2R,4S,5R)-5-Ethenyl-1-azabicyclo[2.2.2]oct-2-yl]-2,3,8,8a-tetrahydro-3aH-furo[2,3-b]indol-3a-ol
Molecular Formula: C19H24N2O2
Molecular Weight: 312.41
Percent Composition: C 73.05%, H 7.74%, N 8.97%, O 10.24%
Literature References: Stereoisomer of quinamine. From bark of Cinchona pubescens Vahl. (C. succirubra Pav.), and C. rosulenta How., Rubiaceae. Isoln: Hesse, Ber. 10, 2158 (1877); Ann. 209, 62 (1881); Oudemans, ibid. 38. Identity with epiquinamine: Culvenor et al., J. Chem. Soc. 1950, 1485.
Properties: Prisms, mp 123°. [a]D15 +200° (alcohol). Slightly sol in water; freely sol in alcohol, chloroform, ether.
Melting point: mp 123°
Optical Rotation: [a]D15 +200° (alcohol)
Status: This monograph has been retired and is no longer subject to revision or update.
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