Corycavamine

Title: Corycavamine
CAS Registry Number: 521-85-7
CAS Name: (14R)-4,6,7,14-Tetrahydro-5,14-dimethylbis[1,3]benzodioxolo[4,5-c:5¢,6¢-g]azecin-13(5H)-one
Additional Names: 7,13-dimethyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one
Molecular Formula: C21H21NO5
Molecular Weight: 367.40
Percent Composition: C 68.65%, H 5.76%, N 3.81%, O 21.77%
Literature References: In Corydalis cava (L.) Schweigg & Korte (C. tuberosa DC.), Fumariaceae: Gadamer et al., Arch. Pharm. 240, 81 (1902). Structure: von Bruchhausen, ibid. 263, 570 (1925). Corycavamine and corycavine originally depicted as the keto and enol tautomers, resp.
Properties: Rhombic columns from ether and alcohol, mp 149°. Is converted to corycavine at the mp. [a]D20 +167° (chloroform). Sol in alcohol and chloroform.
Melting point: mp 149°
Optical Rotation: [a]D20 +167° (chloroform)
Derivative Type: dl-Form
Additional Names: Corycavine
Properties: Orthorhombic plates from alc, mp 218°, mp 222° in vac. Very slightly sol in water; sol in abs alcohol and chloroform; unstable to light.
Melting point: mp 218°; mp 222° in vac
Status: This monograph has been retired and is no longer subject to revision or update.
Corycavidine Corydaldine Corydaline Corydalis Corydine