Crimidine

Title: Crimidine
CAS Registry Number: 535-89-7
CAS Name: 2-Chloro-N,N,6-trimethyl-4-pyrimidinamine
Additional Names: 2-chloro-4-(dimethylamino)-6-methylpyrimidine
Manufacturers' Codes: W-491
Trademarks: Castrix
Molecular Formula: C7H10ClN3
Molecular Weight: 171.63
Percent Composition: C 48.99%, H 5.87%, Cl 20.66%, N 24.48%
Literature References: Prepd from an appropriate 2,4-dihalopyrimidine and dimethylamine: Westphal, US 2219858 (1940 to Winthrop). Toxicology study: K. P. DuBois, J. Am. Pharm. Assoc. Sci. Ed. 37, 307 (1948). Study of pyridoxine as antidote: O. Karlog, E. Knudsen, Nature 200, 790 (1963). HPLTC determn in biological samples: P. De Saqui-Sannes et al., J. Anal. Toxicol. 20, 185 (1996).
Properties: Commercial product is a brown waxy solid, mp 87°. Practically insol in water. Sol in most organic solvents. Poisonous! LD50 in rats, mice, guinea pigs (mg/kg): 1.00 ±0.06, 0.42 ±0.05, 2.66 ±0.10 i.p.; in rats (mg/kg): 1.25 ±0.10 orally (DuBois). LD50 in male, female mice (mg/kg): 1.3, 1.1 s.c.; in female mice (mg/kg): 1.2 orally (Karlog, Knudsen).
Melting point: mp 87°
Toxicity data: LD50 in rats, mice, guinea pigs (mg/kg): 1.00 ±0.06, 0.42 ±0.05, 2.66 ±0.10 i.p.; in rats (mg/kg): 1.25 ±0.10 orally (DuBois); LD50 in male, female mice (mg/kg): 1.3, 1.1 s.c.; in female mice (mg/kg): 1.2 orally (Karlog, Knudsen)
CAUTION: May cause serious CNS damage leading to fatal convulsions.
Use: Rodenticide.
Status: This monograph has been retired and is no longer subject to revision or update.
Croceic Acid Cromolyn Cropropamide Croscarmellose Sodium Crotamiton

Crimidine
Crimidine.png
Identifiers
CAS number 535-89-7
PubChem 10813
KEGG C19138 YesY
Jmol-3D images Image 1
Properties
Molecular formula C7H10ClN3
Molar mass 171.627
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Crimidine is a convulsant poison used as a rodenticide.