Crotamiton

Title: Crotamiton
CAS Registry Number: 483-63-6
CAS Name: N-Ethyl-N-(2-methylphenyl)-2-butenamide
Additional Names: N-ethyl-o-crotonotoluidide; crotonyl-N-ethyl-o-toluidine
Trademarks: Crotamitex (Troponwerke); Eurax (Novartis); Euraxil (Thomae); Veteusan (Veterinaria)
Molecular Formula: C13H17NO
Molecular Weight: 203.28
Percent Composition: C 76.81%, H 8.43%, N 6.89%, O 7.87%
Literature References: Prepd by treating crotonic acid o-toluidide with diethyl sulfate: CH 253472; CH 253473; GB 615137 (1949 to Geigy).
Properties: Yellowish oil, bp13 153-155°. Sol in methanol, ethanol.
Boiling point: bp13 153-155°
Use: Fungicide, insecticide.
Therap-Cat: Scabicide.
Therap-Cat-Vet: Scabicide; antipruritic.
Keywords: Ectoparasiticide.
Crotethamide Croton Oil Crotonaldehyde Crotonic Acid Crotoxin

Crotamiton
Crotamiton.png
Systematic (IUPAC) name
(E)-N-Ethyl-N-(2-methylphenyl)but-2-enamide[1]
Clinical data
AHFS/Drugs.com monograph
Pregnancy cat. C
Legal status  ?
Identifiers
CAS number 483-63-6 YesY
ATCvet code QP53AX04
PubChem CID 688020
DrugBank DB00265
ChemSpider 599515 YesY
UNII D6S4O4XD0H YesY
KEGG D01381 YesY
ChEMBL CHEMBL1200709 N
Chemical data
Formula C13H17NO 
Mol. mass 203.28 g/mol
 N (what is this?)  (verify)

Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug). It is a prescription lotion based medicine that is applied to the whole body to get rid of the scabies parasite that burrows under the skin and causes itching.