Cyclopentamine

Title: Cyclopentamine
CAS Registry Number: 102-45-4
CAS Name: N,a-Dimethylcyclopentaneethanamine
Additional Names: N,a-dimethylcyclopentaneethylamine; 1-cyclopentyl-2-methylaminopropane; b-(methylamino)propylcyclopentane; cyclopentadrine
Trademarks: Sinos; Cyklosal; Cyclonarol (Hœatrol); Clopane (Lilly)
Molecular Formula: C9H19N
Molecular Weight: 141.25
Percent Composition: C 76.53%, H 13.56%, N 9.92%
Literature References: Prepn: Rohrmann, US 2520015 (1950 to Lilly).
Derivative Type: Hydrochloride
CAS Registry Number: 3459-06-1
Molecular Formula: C9H19N.HCl
Molecular Weight: 177.71
Percent Composition: C 60.83%, H 11.34%, N 7.88%, Cl 19.95%
Properties: Crystals, mp 113-115° (base bp30 83-86°, nD25 1.4500). Bitter taste. Freely sol in water.
Melting point: mp 113-115°
Boiling point: base bp30 83-86°
Index of refraction: nD25 1.4500
Therap-Cat: Adrenergic (vasoconstrictor); nasal decongestant.
Keywords: a-Adrenergic Agonist; Decongestant.
Cyclopentane Cyclopentanol Cyclopentanone Cyclopenthiazide Cyclopentobarbital

Cyclopentamine
Cyclopentamine.svg
Systematic (IUPAC) name
(RS)-1-cyclopentyl-N-methyl-propan-2-amine
Clinical data
Legal status Uncontrolled
Routes Inhalation
Identifiers
CAS number 102-45-4
ATC code R01AA02
PubChem CID 7608
ChemSpider 7326 YesY
UNII WB9Q6M8O60 YesY
KEGG D07370 YesY
ChEMBL CHEMBL329203 YesY
Synonyms N,α-dimethyl-cyclopenaneethylamine
Chemical data
Formula C9H19N 
Mol. mass 141.254
Physical data
Boiling point 171 °C (340 °F)
 YesY (what is this?)  (verify)

Cyclopentamine (Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos) is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia, but has now been largely discontinued possibly due to the availability, effectiveness, and safety of a structurally similar drug, propylhexedrine.[citation needed]