Dansyl Chloride

Title: Dansyl Chloride
CAS Registry Number: 605-65-2
CAS Name: 5-(Dimethylamino)-1-naphthalenesulfonyl chloride
Molecular Formula: C12H12ClNO2S
Molecular Weight: 269.75
Percent Composition: C 53.43%, H 4.48%, Cl 13.14%, N 5.19%, O 11.86%, S 11.89%
Literature References: Reagent for fluorescent labelling of amines, amino acids and proteins. Synthesis: G. Weber, Biochem. J. 51, 155 (1952); A. Mendel, J. Chem. Eng. Data 15, 340 (1970). In amino acid analysis: J. Airhart et al., Anal. Biochem. 53, 132 (1973). In HPLC analysis of phenols: R. M. Cassidy, D. S. LeGay, J. Chromatogr. Sci. 12, 85 (1974). In protein microassays: T. Kinoshita et al., Anal. Biochem. 66, 104 (1975). In measurement of desquamation: R. Marks et al., Br. J. Dermatol. 111, 265 (1984).
Properties: Yellow-orange crystals from hexane, mp 66.5-68°. Sol in acetone, pyridine, benzene, dioxane. Insol in water.
Melting point: mp 66.5-68°
Use: In fluorescent labelling, column chromatography, HPLC.
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