Deanol

Title: Deanol
CAS Registry Number: 108-01-0
CAS Name: 2-(Dimethylamino)ethanol
Additional Names: b-dimethylaminoethyl alcohol; N,N-dimethyl-2-hydroxyethylamine
Molecular Formula: C4H11NO
Molecular Weight: 89.14
Percent Composition: C 53.90%, H 12.44%, N 15.71%, O 17.95%
Line Formula: (CH3)2NCH2CH2OH
Literature References: Prepd from equimolar amounts of ethylene oxide and dimethylamine: Knorr, Ber. 37, 3508 (1904); Hanhart, Ingold, J. Chem. Soc. 1927, 1012. Clinical trial in hyperkinetic children: N. Coleman et al., Psychosomatics 17, 68 (1976); in involuntary movement disorders: D. E. Casey, Dis. Nerv. Syst. 38, 7 (1977).
Properties: Liquid. d420 0.8866. bp758 135°. nD20 1.43. Miscible with water, alcohol, ether.
Boiling point: bp758 135°
Index of refraction: nD20 1.43
Density: d420 0.8866
Derivative Type: Aceglumate
CAS Registry Number: 3342-61-8
Trademarks: Clérégil (Merck-Clenot); Risatarun (Ravensberg)
Molecular Formula: C4H11NO.C7H11NO5
Molecular Weight: 278.30
Percent Composition: C 47.47%, H 7.97%, N 10.07%, O 34.49%
Literature References: Prepn: FR M2487 (1964 to Interco Fribourg), C.A. 61, 12085c (1964).
Properties: Sol in water.
Derivative Type: Acetamidobenzoate
CAS Registry Number: 3635-74-3
Trademarks: Deaner (3M Pharma); Pabenol (Gentili)
Molecular Formula: C4H11NO.C9H9NO3
Molecular Weight: 268.31
Percent Composition: C 58.19%, H 7.51%, N 10.44%, O 23.85%
Literature References: Prepn: GB 879259 (1957 to Riker Labs); A. Lasslo et al., J. Am. Pharm. Assoc. Sci. Ed. 48, 345 (1959).
Properties: Crystals from absolute ethanol + ethyl acetate, mp 159-161.5°. Sol in water.
Melting point: mp 159-161.5°
Derivative Type: Bitartrate
CAS Registry Number: 5988-51-2
Trademarks: Liparon (Finadiet)
Molecular Formula: C4H11NO.C4H6O6
Molecular Weight: 239.22
Percent Composition: C 40.17%, H 7.16%, N 5.86%, O 46.82%
Properties: Crystals, sol in water.
Derivative Type: Hemisuccinate
Trademarks: Tonibral (Bouchara); Rischiaril (Piam)
Molecular Formula: C4H11NO.C4H6O4
Molecular Weight: 207.22
Percent Composition: C 46.37%, H 8.27%, N 6.76%, O 38.60%
Properties: White, hygroscopic crystalline powder. Very soluble in water, ethanol; sparingly sol in chloroform, benzene.
Therap-Cat: CNS stimulant.
Keywords: CNS Stimulant.
Debrisoquin Decaborane(14) Decalin? Decamethonium Bromide Decamethylcyclopentasiloxane

Dimethylethanolamine
Skeletal formula of dimethylethanolamine
Identifiers
Abbreviations DMAE, DMEA
CAS number 108-01-0 YesY
PubChem 7902
ChemSpider 13854944 N
UNII 2N6K9DRA24 YesY
EC number 203-542-8
UN number 2051
KEGG D07777 N
MeSH Deanol
ChEBI CHEBI:271436 N
ChEMBL CHEMBL1135 N
RTECS number KK6125000
ATC code N06BX04
Beilstein Reference 1209235
Jmol-3D images Image 1
Properties
Molecular formula C4H11NO
Molar mass 89.14 g mol−1
Appearance Colourless liquid
Odor Fishy, ammoniacal
Density 890 mg mL−1
Melting point −59.00 °C; −74.20 °F; 214.15 K
Boiling point 134.1 °C; 273.3 °F; 407.2 K
log P −0.25
Vapor pressure 816 Pa (at 20 °C)
Acidity (pKa) 9.23 (at 20 °C)[1]
Basicity (pKb) 4.77 (at 20 °C)
Refractive index (nD) 1.4294
Hazards
GHS pictograms The flame pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The corrosion pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word DANGER
GHS hazard statements H226, H302, H312, H314, H332
GHS precautionary statements P280, P305+351+338, P310
EU Index 603-047-00-0
EU classification Corrosive C
R-phrases R10, R20/21/22, R34
S-phrases (S1/2), S25, S26, S36/37/39, S45
Flash point 39 °C; 102 °F; 312 K
Explosive limits 1.4–12.2%
LD50
  • 1.214 g kg−1 (dermal, rabbit)
  • 2 g kg−1 (oral, rat)
Related compounds
Related alkanols
  • N-Methylethanolamine
  • Diethylethanolamine
  • Diethanolamine
  • N,N-Diisopropylaminoethanol
  • Methyl diethanolamine
  • Triethanolamine
  • Bis-tris methane
Related compounds Diethylhydroxylamine
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Dimethylaminoethanol, also known as dimethylethanolamine (DMAE and DMEA respectively), is a primary alcohol. This compound also goes by the names of N,N-dimethyl-2-aminoethanol, beta-dimethylaminoethyl alcohol, beta-hydroxyethyldimethylamine and Deanol. It is a transparent, pale-yellow liquid.