Title: Deptropine
CAS Registry Number: 604-51-3
CAS Name: endo-3-[(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane
Additional Names: 3a-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)oxy]-1aH,5aH-tropane; dibenzheptropine
Molecular Formula: C23H27NO
Molecular Weight: 333.47
Percent Composition: C 82.84%, H 8.16%, N 4.20%, O 4.80%
Literature References: Prepn: Van der Stelt et al., J. Med. Pharm. Chem. 4, 335 (1961). Pharmacology: Funcke et al., Arch. Int. Pharmacodyn. 148, 135 (1964); Timmerman et al., ibid. 187, 291 (1970). Metabolism: Hespe et al., ibid. 164, 397 (1966).
Derivative Type: Citrate
CAS Registry Number: 2169-75-7
Manufacturers' Codes: BS-6987
Trademarks: Brontine (Yamanouchi)
Molecular Formula: C23H27NO.C6H8O7
Molecular Weight: 525.59
Percent Composition: C 66.27%, H 6.71%, N 2.66%, O 24.35%
Properties: LD50 in mice (mg/kg): 32 i.v.; 300 orally (Timmerman).
Toxicity data: LD50 in mice (mg/kg): 32 i.v.; 300 orally (Timmerman)
Derivative Type: Maleate
Molecular Formula: C23H27NO.C4H4O4
Molecular Weight: 449.54
Percent Composition: C 72.14%, H 6.95%, N 3.12%, O 17.80%
Properties: Crystals from ethanol, acetone, ethyl acetate or chloroform, mp 133-136°.
Melting point: mp 133-136°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Other Tricyclics.
Dequalinium Chloride Deracoxib Deramciclane Dermostatin Derris Root

Systematic (IUPAC) name
Clinical data
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CAS number 604-51-3 2169-75-7
ATC code R06AX16
PubChem CID 16576
ChemSpider 16735768 YesY
KEGG D07404 YesY
ChEBI CHEBI:50189 YesY
Chemical data
Formula C23H27NO 
Mol. mass 333.467 g/mol
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Deptropine (Brontina) also known as dibenzheptropine, is an antihistamine with anticholinergic properties. It is usually marketed as the citrate salt.[1]