Desmosterol

Title: Desmosterol
CAS Registry Number: 313-04-2
CAS Name: 3b-Cholesta-5,24-dien-3-ol
Additional Names: 24-dehydrocholesterol; desmesterol
Molecular Formula: C27H44O
Molecular Weight: 384.64
Percent Composition: C 84.31%, H 11.53%, O 4.16%
Literature References: Has been isolated from chick embryos and the skin of rats: Stokes et al., J. Biol. Chem. 220, 415 (1956). From barnacles: Fagerlund, Idler, J. Am. Chem. Soc. 79, 6473 (1957); from red algae: Idler et al., Steroids 11, 465 (1968). Synthesis: Dasgupta et al., J. Org. Chem. 39, 1658 (1974); M. A. Apfel, ibid. 43, 2284 (1978). Stereospecific synthesis: M. Koreeda et al., ibid. 45, 1172 (1980); S. Takano et al., Chem. Commun. 1983, 760.
Properties: Platelets from methanol, mp 121.5°, also reported as 119-119.5°. [a]D27 -41.0° (c = 1 in chloroform).
Melting point: mp 121.5°, also reported as 119-119.5°
Optical Rotation: [a]D27 -41.0° (c = 1 in chloroform)
Desogestrel Desomorphine Desonide Desosamine Desoximetasone

Desmosterol
Desmosterol.png
Identifiers
CAS number 313-04-2 YesY
PubChem 439577
ChemSpider 388662 YesY
ChEBI CHEBI:17737 YesY
ChEMBL CHEMBL455876 YesY
Jmol-3D images Image 1
Properties
Molecular formula C27H44O
Molar mass 384.64 g/mol
Appearance White powder
Melting point 121.5 °C
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Desmosterol is a molecule similar to cholesterol. It is accumulated in desmosterolosis.

In 2014, it was named the Molecule of the Year 2012 by the International Society for Molecular and Cell Biology and Biotechnology Protocols and Researches (ISMCBBPR).[1]