Diampromide

Title: Diampromide
CAS Registry Number: 552-25-0
CAS Name: N-[2-[Methyl(2-phenylethyl)amino]propyl]-N-phenylpropanamide
Additional Names: N-[2-(methylphenethylamino)propyl]propionanilide
Molecular Formula: C21H28N2O
Molecular Weight: 324.46
Percent Composition: C 77.74%, H 8.70%, N 8.63%, O 4.93%
Literature References: Synthesis: Wright et al., J. Am. Chem. Soc. 81, 1518 (1959); US 2944081 (1960 to American Cyanamid).
Properties: Liquid, bp0.5 174-178°. nD26 1.546.
Boiling point: bp0.5 174-178°
Index of refraction: nD26 1.546
Derivative Type: Sulfate
Molecular Formula: C21H30N2O5S
Molecular Weight: 422.54
Percent Composition: C 59.69%, H 7.16%, N 6.63%, O 18.93%, S 7.59%
Properties: Crystals from ethanol + ether, mp 110-111°.
Melting point: mp 110-111°
NOTE: This is a controlled substance (opiate): 21 CFR, 1308.11.
Therap-Cat: Analgesic (narcotic).
Keywords: Analgesic (Narcotic).
Diamthazole Dihydrochloride Diamyl Sodium Sulfosuccinate Dianisidine Diathymosulfone Diatretyne I

Diampromide
Diampromide.svg
Systematic (IUPAC) name
N-[2-(methyl-(2-phenylethyl)amino)propyl]-N-phenylpropanamide
Clinical data
Legal status Prohibited (S9) (AU)
Identifiers
CAS number 552-25-0
ATC code None
PubChem CID 62370
DrugBank DB01502
ChemSpider 56158 YesY
UNII 26G7YC77BU YesY
Synonyms Diampromide
Chemical data
Formula C21H28N2O 
Mol. mass 324.46 g/mol
 YesY (what is this?)  (verify)

Diampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram. It was invented in the 1960s,[1] and can be described as a ring-opened analogue of fentanyl.[1]

Diampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea, and is around the same potency as morphine.[2]