Title: Difluoromethane
CAS Registry Number: 75-10-5
Additional Names: HFC-32; methylene difluoride; R-32
Trademarks: Genetron 32 (Honeywell)
Molecular Formula: CH2F2
Molecular Weight: 52.02
Percent Composition: C 23.09%, H 3.88%, F 73.04%
Literature References: Hydrofluorocarbon refrigerant with zero ozone-depletion potential. Prepn: A. L. Henne, J. Am. Chem. Soc. 59, 1400 (1937). Structural studies: L. O. Brockway, J. Phys. Chem. 41, 185, 747 (1937); W. C. Hamilton, K. Hedberg, J. Am. Chem. Soc. 75, 5529 (1952). Microwave spectrum: D. R. Lide, Jr., ibid. 74, 3548 (1952). UV absorption spectrum: P. Wagner, A. B. F. Duncan, ibid. 77, 2609 (1955). Thermodynamic properties: P. F. Malbrunot et al., J. Chem. Eng. Data 13, 16 (1968); D. R. Defibaugh et al., ibid. 39, 333 (1994). Viscosity study: M. Takahashi et al., ibid. 40, 900 (1995). Toxicology and metabolism in rats: M. K. Ellis et al., Fundam. Appl. Toxicol. 31, 243 (1996).
Properties: Colorless gas, bp -51.6°. mp -136°. d0 (liq) 1.052. d25 (liq) 0.961. Critical temp 78.4°; critical press 57.54 atm; critical d 0.430. Dipole moment 1.98 D.
Melting point: mp -136°
Boiling point: bp -51.6°
Density: d0 (liq) 1.052; d25 (liq) 0.961; d 0.430
Use: Refrigerant.
Difluprednate Digallic Acid Digalogenin Diginatigenin Diginatin

Stereo skeletal formula of difluoromethane with all explicit hydrogens added Spacefill model of difluoromethane
Abbreviations HFC-32


CAS number 75-10-5 YesY
PubChem 6345
ChemSpider 6105 YesY
EC number 200-839-4
UN number 3252
MeSH Difluoromethane
ChEBI CHEBI:47855 YesY
RTECS number PA8537500
Beilstein Reference 1730795
Gmelin Reference 259463
Jmol-3D images Image 1
Molecular formula CH2F2
Molar mass 52.02 g mol−1
Appearance Colorless gas
Density 1.1 g cm-3
Melting point −136 °C; −213 °F; 137 K
Boiling point −52 °C; −62 °F; 221 K
log P -0.611
Vapor pressure 1518.92 kPa (at 21.1 °C)
MSDS External MSDS
EU classification Flammable F
R-phrases R11
S-phrases S9, S16, S33
NFPA 704
NFPA 704.svg
Autoignition temperature 648 °C
Supplementary data page
Structure and
n, εr, etc.
Phase behaviour
Solid, liquid, gas
Spectral data UV, IR, NMR, MS
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Difluoromethane, also called HFC-32 or R-32, is an organic compound of the dihalogenoalkane variety. It is based on methane, except that two of the four hydrogen atoms have been replaced by fluorine atoms. Hence the formula is CH2F2 instead of CH4 for normal methane.