Dihydroequilin

Title: Dihydroequilin
CAS Registry Number: 3563-27-7
CAS Name: (17b)-Estra-1,3,5(10),7-tetraene-3,17-diol
Molecular Formula: C18H22O2
Molecular Weight: 270.37
Percent Composition: C 79.96%, H 8.20%, O 11.84%
Literature References: Occurs in the 17a- and 17b-forms. Prepn of b-form by reduction of equilin with sodium in alc: David, Acta Brev. Nederland 4, 63 (1934); Serini et al., US 2221340 (1940 to Schering). Isoln of b-form from pregnant mares' urine: Gaudry, Glen, Ind. Chim. Belge Suppl. 2, 435 (1959). Prepn of a-form by reduction of equilin with aluminum isopropoxide: Carol et al., J. Biol. Chem. 185, 267 (1950). Isoln of a-form from pregnant mares' urine: Glen et al., Nature 177, 753 (1956). a-Form was formerly called b-dihydroequilin and vice versa: Banes et al., J. Biol. Chem. 187, 557 (1950).
Properties: Crystals from actone, mp 174.5-174.6°. [a]D20 +220° (dioxane).
Melting point: mp 174.5-174.6°
Optical Rotation: [a]D20 +220° (dioxane)
Derivative Type: 17a-Form
CAS Registry Number: 651-55-8
Properties: Plates from 30% ethanol, mp 205.5-205.6°. [a]D20 +213° (ethanol).
Melting point: mp 205.5-205.6°
Optical Rotation: [a]D20 +213° (ethanol)
Dihydroisocodeine Dihydromorphine Dihydroresorcinol Dihydrostreptomycin Dihydrotachysterol