Dihydrotachysterol

Title: Dihydrotachysterol
CAS Registry Number: 67-96-9
CAS Name: (3b,5E,7E,10a,22E)-9,10-Secoergosta-5,7,22-trien-3-ol
Additional Names: dichystrolum; anti-tetany substance 10; AT 10
Trademarks: Antitanil; Calcamine (Wander); Dygratyl (Ferrosan); Dihydral (Duphar); Hytakerol (Winthrop); Parterol; Tachyrol (Duphar)
Molecular Formula: C28H46O
Molecular Weight: 398.66
Percent Composition: C 84.36%, H 11.63%, O 4.01%
Literature References: Prepn by reduction of tachysterol: Windaus et al., Ann. 499, 198 (1932); v. Werder, US 2228491 (1941 to Winthrop), cf. Z. Physiol. Chem. 260, 119 (1939). Activity similar to parathyroid extract.
Properties: Needles from 90% methanol, mp 125-127°. [a]D22 +97.5° (chloroform). uv max: 242, 251, 261 nm (E1%1cm 870, 1010, 650). Insol in water. Easily sol in organic solvents.
Melting point: mp 125-127°
Optical Rotation: [a]D22 +97.5° (chloroform)
Absorption maximum: uv max: 242, 251, 261 nm (E1%1cm 870, 1010, 650)
Therap-Cat: Calcium regulator.
Keywords: Calcium Regulator.
Dihydrothebaine Dihydroxyaluminum Acetylsalicylate Dihydroxyaluminum Aminoacetate Dihydroxyaluminum Sodium Carbonate Dihydroxymaleic Acid

Dihydrotachysterol
Dihydrotachysterol.png
Systematic (IUPAC) name
(1S,3E,4S)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-Dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylcyclohexan-1-ol
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a682335
Legal status  ?
Identifiers
CAS number 67-96-9 YesY
ATC code A11CC02
PubChem CID 5311071
DrugBank DB01070
ChemSpider 4470607 YesY
UNII R5LM3H112R YesY
KEGG D00299 YesY
ChEBI CHEBI:4591 YesY
Chemical data
Formula C28H46O 
Mol. mass 398.664 g/mol
 YesY (what is this?)  (verify)

Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.[1]