Diisopromine

Title: Diisopromine
CAS Registry Number: 5966-41-6
CAS Name: N,N-Bis(1-methylethyl)-g-phenylbenzenepropanamine
Additional Names: N,N-diisopropyl-3,3-diphenylpropylamine; 1,1-diphenyl-3-diisopropylaminopropane; disopromine
Molecular Formula: C21H29N
Molecular Weight: 295.46
Percent Composition: C 85.37%, H 9.89%, N 4.74%
Literature References: Prepn: GB 808158 (1959 to N. V. Nederland. Comb. voor Chem. Ind. and Janssen, N. V.).
Derivative Type: Hydrochloride
CAS Registry Number: 24358-65-4
Trademarks: Agofell (Janssen); Bilagol (Janssen)
Molecular Formula: C21H29N.HCl
Molecular Weight: 331.92
Percent Composition: C 75.99%, H 9.11%, N 4.22%, Cl 10.68%
Properties: Crystals, mp 175-176°. uv max: 254, 259.5, 268.8 nm. Soluble in water, methanol, ethanol, chloroform. Practically insol in ether, aq solns of alkalies and ammonia.
Melting point: mp 175-176°
Absorption maximum: uv max: 254, 259.5, 268.8 nm
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.
Status: This monograph has been retired and is no longer subject to revision or update.
Diisopropanolamine Diisopropyl Paraoxon Diisopropylamine Diisopropylamine Dichloroacetate Dikegulac

Diisopromine
Diisopromine.svg
Systematic (IUPAC) name
N,N-diisopropyl-3,3-diphenylpropan-1-amine
Clinical data
Legal status  ?
Identifiers
CAS number 5966-41-6 YesY
ATC code A03AX02
PubChem CID 22262
ChemSpider 20899 YesY
UNII 2825S6AW9U YesY
KEGG D07092 YesY
Chemical data
Formula C21H29N 
Mol. mass 295.462 g/mol
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Diisopromine or disoprominum, usually as the hydrochloride salt, is a synthetic spasmolytic which neutralizes spastic conditions of the biliary tract and of the sphincter of Oddi. It was discovered at Janssen Pharmaceutica in 1955.