Diphacinone

Title: Diphacinone
CAS Registry Number: 82-66-6
CAS Name: 2-(Diphenylacetyl)-1H-indene-1,3(2H)-dione
Additional Names: 2-diphenylacetyl-1,3-diketohydrindene; 2-diphenylacetyl-1,3-indandione; diphenadione
Manufacturers' Codes: U-1363
Trademarks: Diphacin (Hacco); Ditrac (Bell); Ramik (Hacco)
Molecular Formula: C23H16O3
Molecular Weight: 340.37
Percent Composition: C 81.16%, H 4.74%, O 14.10%
Literature References: Anticoagulant; inhibits vitamin K-dependent synthesis of factors II, VII and X. Prepn: D. G. Thomas, US 2672483 (1954 to Upjohn). Anticoagulant effects in rodents: J. T. Correll et al., Proc. Soc. Exp. Biol. Med. 80, 139 (1952). Metabolism in rats and mice: C. C. Yu et al., Drug Metab. Dispos. 10, 645 (1982). LC/MS determn in commercial rodenticides: M. Z. Mesmer, R. A. Flurer, J. Chromatogr. A 891, 249 (2000).
Properties: Pale yellow crystals from ethanol, mp 146-147°. Practically insol in water. Slightly sol in benzene, hot ethanol. Sol in acetone, acetic acid. LD50 orally (mg/kg): 3 in rats; 340 in mice; 35 in rabbits (Correll).
Melting point: mp 146-147°
Toxicity data: LD50 orally (mg/kg): 3 in rats; 340 in mice; 35 in rabbits (Correll)
Use: Rodenticide.
Diphemanil Methylsulfate Diphemethoxidine Diphenamid Diphenane Diphencyprone

Diphenadione
Diphenadione racemate.svg
Diphenadione ball-and-stick.png
Identifiers
CAS number 82-66-6 YesY
PubChem 6719
ChemSpider 6463
UNII 54CA01C6JX YesY
KEGG D07136 YesY
ChEMBL CHEMBL1413199
ATC code B01AA10
Jmol-3D images Image 1
Properties
Molecular formula C23H16O3
Molar mass 340.37 g mol−1
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Diphenadione is a vitamin K antagonist which has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents. This chemical compound is an anti-coagulant with longer activity than warfarin and other synthetic indandione anticoagulants.[1]