Diphemethoxidine

Title: Diphemethoxidine
CAS Registry Number: 13862-07-2
CAS Name: 2-(Diphenylmethyl)-1-piperidineethanol
Additional Names: 2-benzhydryl-1-piperidineethanol; 1-(b-hydroxyethyl)-2-(diphenylmethyl)piperidine
Manufacturers' Codes: Ba-18189
Trademarks: Cleofil (Ciba)
Molecular Formula: C20H25NO
Molecular Weight: 295.42
Percent Composition: C 81.31%, H 8.53%, N 4.74%, O 5.42%
Literature References: Prepn: GB 861815 (1961 to Ciba), C.A. 55, 15517h (1961).
Properties: mp 106-107°. bp0.1 180-181°.
Melting point: mp 106-107°
Boiling point: bp0.1 180-181°
Derivative Type: Hydrochloride
Properties: mp 166-167°.
Melting point: mp 166-167°
Therap-Cat: Anorexic.
Keywords: Anorexic.
Status: This monograph has been retired and is no longer subject to revision or update.
Diphenamid Diphenane Diphencyprone Diphenic Acid Diphenidol

Difemetorex
Difemetorex.png
Systematic (IUPAC) name
2-[2-(diphenylmethyl)piperidin-1-yl]ethanol
Clinical data
Legal status Withdrawn
Routes Oral
Identifiers
CAS number 13862-07-2
ATC code None
PubChem CID 65607
ChemSpider 59048
UNII O0417MPF6W YesY
Chemical data
Formula C20H25NO 
Mol. mass 295.42 g/mol

Difemetorex (INN; sold as Cleofil), also known as diphemethoxidine, is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use.[1][2][3][4][5] It was introduced in France by Ciba-Geigy in 1966 but is now no longer marketed.[6]