Dipin

Title: Dipin
CAS Registry Number: 738-99-8
CAS Name: 1,4-Bis[bis(1-aziridinyl)phosphinyl]piperazine
Additional Names: 1,4-piperazinediylbis[bis(1-aziridinyl)phosphine oxide]; piperazine-1,4-bis(N,N¢-diethylenephosphonediamide); tetraethyleneimidopiperazine-N,N¢-diphosphoric acid
Molecular Formula: C12H24N6O2P2
Molecular Weight: 346.31
Percent Composition: C 41.62%, H 6.99%, N 24.27%, O 9.24%, P 17.89%
Literature References: Alkylating agent; exptl antineoplastic. Prepn: Kropacheva et al., Zh. Obshch. Khim. 30, 3584 (1960), C.A. 55, 18695c (1961). Spectrophotometric determn: L. Kh. Kartashova, E. M. Salomatin, Farmatsiya (Moscow) 33, 72 (1983), C.A. 102, 119736j (1985). Metabolism in rats: V. V. Chistyakov et al., Khim. Farm. Zh. 21, 398 (1987), C.A. 107, 146734s (1987).
Properties: Crystals, mp 187°.
Melting point: mp 187°
Dipipanone Dipiproverine Dipivefrin Diploicin Diponium Bromide