Title: Disulfoton
CAS Registry Number: 298-04-4
CAS Name: Phosphorodithioic acid O,O-diethyl S-[2-(ethylthio)ethyl] ester
Additional Names: O,O-diethyl-S-ethylmercaptoethyl dithiophosphate; thiodemeton; dithiodemeton
Manufacturers' Codes: Bay 19639; ENT-23347
Trademarks: Di-Syston (Bayer CropSci.)
Molecular Formula: C8H19O2PS3
Molecular Weight: 274.40
Percent Composition: C 35.02%, H 6.98%, O 11.66%, P 11.29%, S 35.06%
Literature References: Homolog of phorate, q.v. Prepn: Schrader, Lorenz, US 2759010; GB 797307 (1956, 1958 both to Bayer). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Review of toxicology and human exposure: Toxicological Profile for Disulfoton (PB95-264347, 1995) 239 pp.
Properties: Colorless oil, bp0.01 108°, bp1.5 132-133°. d420 1.144. nD20 1.5348. Vapor pressure at 20°: 1.8 ´ 10-4 mm Hg. Insol in water. LD50 in female, male rats (mg/kg): 2.3, 6.8 orally; 6, 15 dermally (Gaines).
Boiling point: bp0.01 108°; bp1.5 132-133°
Index of refraction: nD20 1.5348
Density: d420 1.144
Toxicity data: LD50 in female, male rats (mg/kg): 2.3, 6.8 orally; 6, 15 dermally (Gaines)
CAUTION: Potential symptoms of overexposure are irritation of eyes, skin; nausea, vomiting, abdominal cramps, diarrhea, salivation; headache, giddiness, vertigo, weakness; rhinorrhea, chest tightness; blurred vision, miosis; cardiac irregularity; muscle fasciculations; dyspnea; eye and skin burns. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 124.
Use: Insecticide.
Disul-sodium Dita Bark Ditazol Di-tert-butyl Ether Di-tert-butyl Malonate

Disulfoton Structural Formulae .V.1.svg
CAS number 298-04-4 YesY
PubChem 3118
ChemSpider 3006 YesY
KEGG C18400 YesY
ChEBI CHEBI:38661 YesY
Jmol-3D images Image 1
Molecular formula C8H19O2PS3
Molar mass 274.404
Appearance Oily, colorless to yellow liquid with a characteristic, sulfur odor
Density 1.14 g/mL
Main hazards Toxic
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Disulfoton is an organophosphate acetylcholinesterase inhibitor used as an insecticide. It is manufactured under the name Di-Syston by Bayer CropScience.

The use of the substance has been restricted by the US government. Bayer, the manufacturer, exited the US market December 31, 2009.[1]