Doxenitoin

Title: Doxenitoin
CAS Registry Number: 3254-93-1
CAS Name: 5,5-Diphenyl-4-imidazolidinone
Additional Names: 5,5-diphenyltetrahydroglyoxalin-4-one; tetrahydro-4-oxo-5,5-diphenylglyoxaline
Manufacturers' Codes: SKF-2599
Trademarks: Glior
Molecular Formula: C15H14N2O
Molecular Weight: 238.28
Percent Composition: C 75.61%, H 5.92%, N 11.76%, O 6.71%
Literature References: Prepd by the reduction of diphenylthiohydantoin with sodium: Biltz, Seydel, Ann. 391, 218 (1912); with Raney nickel: Whalley et al., J. Am. Chem. Soc. 77, 745 (1955); Goodman, US 2744852 (1956).
Properties: Stout plates from methanol, mp 183° (Goodman); crystals from alc, mp 185.5-186.5° (Biltz). Moderately sol in glacial acetic acid; less sol in alc, ethyl acetate, benzene, chloroform. Practically insol in water, ligroin.
Melting point: mp 183° (Goodman); mp 185.5-186.5° (Biltz)
Derivative Type: Hydrochloride
Molecular Formula: C15H14N2O.HCl
Molecular Weight: 274.75
Percent Composition: C 65.57%, H 5.50%, N 10.20%, O 5.82%, Cl 12.90%
Properties: Dec 205-206°.
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant.
Status: This monograph has been retired and is no longer subject to revision or update.
Doxepin Doxercalciferol Doxifluridine Doxofylline DPQ