Droprenilamine

Title: Droprenilamine
CAS Registry Number: 57653-27-7
CAS Name: N-(2-Cyclohexyl-1-methylethyl)-g-phenylbenzenepropanamine
Additional Names: (±)-N-(3,3-diphenylpropyl)-a-methylcyclohexaneethylamine; droprenylamine
Molecular Formula: C24H33N
Molecular Weight: 335.53
Percent Composition: C 85.91%, H 9.91%, N 4.17%
Literature References: Vasodilator with antiarrhythmic and hypotensive activity. Prepn: M. Carissimi et al., DE 2521113 (1976 to Maggioni), C.A. 84, 164388t (1976). Synthesis and pharmacological study: G. Carenini et al., Arzneim.-Forsch. 26, 2127 (1976). Hemodynamic and metabolic effects: R. J. Marshall, J. R. Parratt, Br. J. Pharmacol. 59, 311 (1977). Clinical evaluation: F. Rengo et al., G. Ital. Cardiol. 10, 473 (1980).
Derivative Type: Hydrochloride
CAS Registry Number: 59182-63-7
Manufacturers' Codes: MG-8926
Trademarks: Valcor (Maggioni)
Molecular Formula: C24H33N.HCl
Molecular Weight: 371.99
Percent Composition: C 77.49%, H 9.21%, N 3.77%, Cl 9.53%
Properties: Crystals from isopropanol, mp 175-176°. LD50 in mice (mg/kg): 2850 orally; 68 i.p. (Carenini).
Melting point: mp 175-176°
Toxicity data: LD50 in mice (mg/kg): 2850 orally; 68 i.p. (Carenini)
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary).
Dropropizine Drosera Drosophilin A Drotaverine Drotebanol