Dyclonine

Title: Dyclonine
CAS Registry Number: 586-60-7
CAS Name: 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone
Additional Names: 3-piperidino-4¢-butoxypropiophenone; b-piperidinoethyl-4-butoxyphenyl ketone; 4-butoxy-b-piperidinopropiophenone; 4-n-butoxy-b-(1-piperidyl)propiophenone; 4-butoxyphenyl piperidineethyl ketone; 2-(1-piperidyl)ethyl p-butoxyphenyl ketone
Molecular Formula: C18H27NO2
Molecular Weight: 289.41
Percent Composition: C 74.70%, H 9.40%, N 4.84%, O 11.06%
Literature References: Prepd from p-butoxyacetophenone by condensation with formaldehyde and piperidine hydrochloride: Pofft, Chem. Tech. (Berlin) 4, 241 (1952), C.A. 47, 10531 (1953).
Derivative Type: Hydrochloride
CAS Registry Number: 536-43-6
Trademarks: Dyclone (Dow); Tanaclone (Amsa)
Molecular Formula: C18H27NO2.HCl
Molecular Weight: 325.87
Percent Composition: C 66.34%, H 8.66%, N 4.30%, O 9.82%, Cl 10.88%
Properties: Crystals, mp 175-176°. Sol in water, alc, acetone. Phenol coefficient 3.6.
Melting point: mp 175-176°
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).
Dydrogesterone Dymanthine Dymixal? Dynamin Dynel

Dyclonine
Dyclonine.png
Systematic (IUPAC) name
1-(4-butoxyphenyl)-3-(1-piperidyl)propan-1-one
Clinical data
Trade names Sucrets
AHFS/Drugs.com monograph
Pregnancy cat. C (US)
Legal status OTC (US)
Routes Lozenge
Identifiers
CAS number 586-60-7 YesY
ATC code N01BX02 R02AD04
PubChem CID 3180
DrugBank DB00645
ChemSpider 3068 YesY
UNII 078A24Q30O YesY
KEGG D07881 YesY
ChEBI CHEBI:4724 YesY
ChEMBL CHEMBL1201217 N
Chemical data
Formula C18H27NO2 
Mol. mass 289.413 g/mol
 N (what is this?)  (verify)

Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge.[1] It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt.[2]