Enilconazole

Title: Enilconazole
CAS Registry Number: 35554-44-0
CAS Name: 1-[2-(2,4-Dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole
Additional Names: (±)-1-[b-(allyloxy)-2,4-dichlorophenethyl]imidazole; imazalil
Manufacturers' Codes: R-23979
Trademarks: Clinafarm (Janssen); Imaverol (Janssen)
Molecular Formula: C14H14Cl2N2O
Molecular Weight: 297.18
Percent Composition: C 56.58%, H 4.75%, Cl 23.86%, N 9.43%, O 5.38%
Literature References: Broad spectrum antimycotic with agricultural and veterinary applications. Prepn: E. F. Godefroi, J. L. Schuermans, DE 2063857; eidem, US 3658813 (1971, 1972 both to Janssen). Efficacy vs citrus decay: P. R. Harding, Plant Dis. Rep. 60, 643 (1976); S. Ben-Yehoshua et al., Pestic. Sci. 12, 485 (1981). Biological and toxicological properties: D. Thienpont et al., Arzneim.-Forsch. 31, 309 (1981). Residue analysis in treated grapefruit: E. R. Stein et al., J. Environ. Sci. Health B16, 427 (1981).
Properties: Solidified oil. Slightly sol in organic solvents; poorly sol in water.
Use: As a disinfectant for stable and kennel equipment; exptly as an agricultural fungicide.
Therap-Cat: Antifungal.
Therap-Cat-Vet: Antifungal.
Keywords: Antifungal (Synthetic); Imidazoles.
Eniluracil Enniatins Enocitabine Enoxacin Enoxaparin

Enilconazole
Imazalil.svg
Identifiers
CAS number 35554-44-0 YesY
PubChem 37175
ChemSpider 34116 YesY
UNII 6K0NOF3XQ6 YesY
KEGG D03997 YesY
ChEMBL CHEMBL356918 YesY
ATCvet code QD01AC90
Jmol-3D images Image 1
Properties
Molecular formula C14H14Cl2N2O
Molar mass 297.18 g mol−1
Appearance Slightly yellow to brown solidified oil[1]
Density 1.23 g/mL
Melting point 50 °C; 122 °F; 323 K ([1])
Boiling point 347 °C; 657 °F; 620 K ([2])
Solubility in water 1400 mg/L (20 °C)[1]
Hazards
Flash point 181 °C (358 °F)[2]
LD50 227 mg/kg (oral rat)
4200 mg/kg (dermal, rabbit)
16 mg/l/4 h (inhalation, rat)[2]
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Enilconazole (synonyms imazalil, chloramizole) is a fungicide widely used in agriculture, particularly in the growing of citrus fruits.[3] Trade names include Freshgard, Fungaflor, and Nuzone.

Enilconazole is also used in veterinary medicine as a topical antimycotic.[4]