Etafedrine

Title: Etafedrine
CAS Registry Number: 7681-79-0
CAS Name: a-[1-(Ethylmethylamino)ethyl]benzenemethanol
Additional Names: l-N-ethylephedrine; l-a-[1-(ethylmethylamino)ethyl]benzyl alcohol; 2-methylethylamino-1-phenyl-1-propanol
Trademarks: Menetryl; Novedrin
Molecular Formula: C12H19NO
Molecular Weight: 193.29
Percent Composition: C 74.57%, H 9.91%, N 7.25%, O 8.28%
Literature References: b-Adrenergic agonist. Prepn: Skita, Keil, Ber. 63, 34 (1930); Ueda et al., Pharm. Bull. 3, 465 (1955).
Derivative Type: Hydrochloride
CAS Registry Number: 5591-29-7
Trademarks: Nethamine (HMR)
Molecular Formula: C12H19NO.HCl
Molecular Weight: 229.75
Percent Composition: C 62.73%, H 8.77%, N 6.10%, O 6.96%, Cl 15.43%
Properties: Crystals from acetone + alcohol, mp 183-184°. One gram dissolves in 1.5 ml water, 8.0 ml alcohol. Aq solns are very stable.
Melting point: mp 183-184°
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.
Etafenone Etamiphyllin Etamycin Etanercept Etanidazole

Etafedrine
Etafedrine Structural Formulae (1R,2S).png
Systematic (IUPAC) name
(1R,2S)-N-ethyl-N-methyl-2-amino-1-phenylpropan-1-ol
Clinical data
Legal status  ?
Identifiers
CAS number 7681-79-0
ATC code None
PubChem CID 10734
ChemSpider 85308
UNII 2Y6VQU63E8 YesY
Chemical data
Formula C12H19NO 
Mol. mass 193.285 g/mol
 YesY (what is this?)  (verify)

Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has the brand name Nethaprin. It was previously commercially available as both the free base and as the hydrochloride salt from Sanofi-Aventis but is now no longer marketed.