Etafenone

Title: Etafenone
CAS Registry Number: 90-54-0
CAS Name: 1-[2-[2-(Diethylamino)ethoxy]phenyl]-3-phenyl-1-propanone
Additional Names: 2¢-[2-(diethylamino)ethoxy]-3-phenylpropiophenone; o-diethylaminoethoxy-b-phenylpropiophenone; 2¢-(b-diethylaminoethoxy)-3-phenylpropiophenone; b-phenyl-o-(diethylaminoethoxy)propiophenone
Manufacturers' Codes: LG-11457
Molecular Formula: C21H27NO2
Molecular Weight: 325.44
Percent Composition: C 77.50%, H 8.36%, N 4.30%, O 9.83%
Literature References: Prepn: G. DiPaco, S. C. Tauro, Ann. Chim. (Rome) 48, 1215 (1958); eidem, DE 1265758 (1968 to Guidotti), C.A. 69, 58950a (1968). Toxicity data: H.-J. Hapke, W. Sterner, Arzneim.-Forsch. 19, 1664 (1969). Series of articles on pharmacology, toxicology, metabolism: ibid. 1664-1681.
Properties: Liquid, bp30 264-268°.
Boiling point: bp30 264-268°
Derivative Type: Hydrochloride
Additional Names: Hetaphenone
Trademarks: Asamedol (Maruko); Baxacor (Mack, Illert.); Corodilan (Meiji); Dialicor (Kissei); Pagano-Cor (Helopharm); Relicor
Molecular Formula: C21H27NO2.HCl
Molecular Weight: 361.91
Percent Composition: C 69.69%, H 7.80%, N 3.87%, O 8.84%, Cl 9.80%
Properties: Crystals, mp 129-130°. LD50 in rats (mg/kg): 716 orally; 20.8 i.v. (Hapke, Sterne).
Melting point: mp 129-130°
Toxicity data: LD50 in rats (mg/kg): 716 orally; 20.8 i.v. (Hapke, Sterne)
Therap-Cat: Vasodilator (coronary).
Keywords: Calcium Channel Blocker; Vasodilator (Coronary).
Etamiphyllin Etamycin Etanercept Etanidazole Etaqualone

Etafenone
Etafenone.svg
Systematic (IUPAC) name
1-(3-{2-[2-(diethylamino)ethoxy]phenyl}phenyl)propan-1-one
Clinical data
Legal status  ?
Identifiers
CAS number 2192-21-4 YesY
ATC code C01DX07
PubChem CID 66659
UNII 0I14K589E7 YesY
KEGG D01440 YesY
Chemical data
Formula C21H27NO2 
Mol. mass 325.44 g/mol
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Etafenone is a vasodilator.