Ethiazide

Title: Ethiazide
CAS Registry Number: 1824-58-4
CAS Name: 6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Additional Names: 6-chloro-3-ethyl-3,4-dihydro-7-sulfamoylbenzo-1,2,4-thiadiazine 1,1-dioxide; 3-ethyl-3,4-dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine 1,1-dioxide; acthiazidum
Molecular Formula: C9H12ClN3O4S2
Molecular Weight: 325.79
Percent Composition: C 33.18%, H 3.71%, Cl 10.88%, N 12.90%, O 19.64%, S 19.68%
Literature References: Prepn: Close et al., J. Am. Chem. Soc. 82, 1132 (1960); Topliss et al., J. Org. Chem. 26, 3842 (1961); GB 861367 (1961 to Ciba).
Properties: Crystals from tetrahydrofuran + chloroform, mp 269-270°.
Melting point: mp 269-270°
NOTE: Component of Hypertane.
Therap-Cat: Diuretic.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.
Status: This monograph has been retired and is no longer subject to revision or update.
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