Title: Ethion
CAS Registry Number: 563-12-2
CAS Name: Phosphorodithioic acid S,S¢-methylene O,O,O¢,O¢-tetraethyl ester
Additional Names: ethyl methylene phosphorodithioate; O,O,O¢,O¢-tetraethyl S,S¢-methylenediphosphorodithioate; bis[S-(diethoxyphosphinothioyl)mercapto]methane; diethion
Manufacturers' Codes: ENT-24105; FMC-1240; Niagara 1240
Trademarks: Commando (Boehringer, Ing.); Rhodocide (Aventis); Tafethion (Rallis)
Molecular Formula: C9H22O4P2S4
Molecular Weight: 384.48
Percent Composition: C 28.11%, H 5.77%, O 16.65%, P 16.11%, S 33.36%
Literature References: Cholinesterase inhibitor. Prepn: Willard, Henahan, US 2873228; US 3014058 (1959, 1961 both to FMC). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Review of toxicology and human exposure: Toxicological Profile for Ethion (PB2000-108024, 2000) 218 pp.
Properties: Liquid, mp -13 to -12°. d420 1.220. nD20 1.5490. Vapor pressure: 1.5 ´ 10-6 mm Hg. Sol in xylene, methylated naphthalene, chloroform, acetone and kerosene + 1% methyl ethyl ketone or benzene; slightly sol in water. LD50 in female, male rats (mg/kg): 27, 65 orally; 62, 245 dermally (Gaines).
Melting point: mp -13 to -12°
Index of refraction: nD20 1.5490
Density: d420 1.220
Toxicity data: LD50 in female, male rats (mg/kg): 27, 65 orally; 62, 245 dermally (Gaines)
CAUTION: Potential symptoms of overexposure are eye, skin irritation; nausea, vomiting, abdominal cramps, diarrhea, salivation; headache, giddiness, vertigo, weakness; rhinorrhea, chest tightness; blurred vision, miosis; cardiac irregularities; muscle fasciculations; dyspnea. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 130.
Use: Insecticide; acaricide.
Therap-Cat-Vet: Ectoparasiticide.
Ethionamide Ethionine Ethiozin Ethiprole Ethirimol

CAS number 563-12-2 YesY
PubChem 3286
ChemSpider 3171 YesY
KEGG C18725 YesY
ChEBI CHEBI:38663 YesY
Jmol-3D images Image 1
Molecular formula C9H22O4P2S4
Molar mass 384.48 g/mol
Appearance Colorless to amber-colored, odorless liquid
Density 1.22 g/cm3
Melting point −12.2 °C; 10.0 °F; 260.9 K
Boiling point 150 °C; 302 °F; 423 K
Main hazards Combustible[1]
Flash point 176.1 °C; 349.0 °F; 449.2 K
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Ethion (C9H22O4P2S4) is an organophosphate insecticide. Ethion is known to affect a neural enzyme called acetylcholinesterase and prevent it from working.