Ethiprole

Title: Ethiprole
CAS Registry Number: 181587-01-9
CAS Name: 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile
Additional Names: 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-ethylsulfinylpyrazole
Manufacturers' Codes: RPA-107382
Trademarks: Curbix (Bayer CropSci.); Kirappu (Bayer CropSci.)
Molecular Formula: C13H9Cl2F3N4OS
Molecular Weight: 397.20
Percent Composition: C 39.31%, H 2.28%, Cl 17.85%, F 14.35%, N 14.11%, O 4.03%, S 8.07%
Literature References: Insecticidal phenylpyrazole; analog of fipronil, q.v. Prepn: C. L. Haas et al., WO 9722593 (1997 to Rhone-Poulenc Agrochimie). Field trial vs stored-grain insects: F. H. Arthur, J. Econ. Entomol. 95, 1314 (2002). Photochemistry, metabolism and GABAergic action compared with fipronil: P. Caboni et al., J. Agric. Food Chem. 51, 7055 (2003).
Properties: mp ~174°. LD50 in house flies (24 hr topical): 0.50 ±0.03 mg/g (Caboni).
Melting point: mp ~174°
Toxicity data: LD50 in house flies (24 hr topical): 0.50 ±0.03 mg/g
Use: Insecticide for chewing and sucking insects.
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