Ethirimol

Title: Ethirimol
CAS Registry Number: 23947-60-6
CAS Name: 5-Butyl-2-(ethylamino)-6-methyl-4(1H)-pyrimidinone
Additional Names: 2-ethylamino-4-methyl-5-n-butyl-6-hydroxypyrimidine
Manufacturers' Codes: PP-149
Trademarks: Milstem (Zeneca); Milgo (Zeneca); Milcurb Super (Zeneca)
Molecular Formula: C11H19N3O
Molecular Weight: 209.29
Percent Composition: C 63.13%, H 9.15%, N 20.08%, O 7.64%
Literature References: Prepn: B. K. Snell et al., ZA 6701373; eidem, US 3980781 (1968, 1976 both to ICI). Systemic fungicidal activity: R. M. Bebbington, Chem. Ind. (London) 1969, 1512; K. J. Bent, Ann. Appl. Biol. 66, 103 (1970). Metabolism and mode of action: A. Calderbank, Acta Phytopathol. 6, 355 (1971).
Properties: Crystalline solid, mp 159-160°. Vapor pressure at 25°: 2 ´ 10-6 mm Hg. Soly in water at 25°: 200 mg/l. Sol in chloroform, trichloroethylene, aq solns of strong acids and bases. Slightly sol in ethanol; sparingly sol in acetone. LD50 orally in rats: 4000 mg/kg (Bebbington).
Melting point: mp 159-160°
Toxicity data: LD50 orally in rats: 4000 mg/kg (Bebbington)
Use: Fungicide.
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