Ethoxzolamide

Title: Ethoxzolamide
CAS Registry Number: 452-35-7
CAS Name: 6-Ethoxy-2-benzothiazolesulfonamide
Additional Names: ethoxyzolamide
Trademarks: Ethamide (Allergan); Glaucotensil (Farmila)
Molecular Formula: C9H10N2O3S2
Molecular Weight: 258.32
Percent Composition: C 41.85%, H 3.90%, N 10.84%, O 18.58%, S 24.83%
Literature References: Carbonic anhydrase inhibitor. Prepn: GB 795174; J. Korman, US 2868800 (1958, 1959 both to Upjohn).
Properties: Crystals from ethyl acetate + Skellysolve B, mp 188-190.5°.
Melting point: mp 188-190.5°
Therap-Cat: Diuretic.
Therap-Cat-Vet: Diuretic.
Keywords: Carbonic Anhydrase Inhibitor; Diuretic; Sulfonamide Derivatives.
Ethybenztropine Ethyl Acetate Ethyl Acetoacetate Ethyl Acrylate Ethyl Alcohol, Denatured

Ethoxzolamide
Ethoxzolamide structure.svg
Ethoxzolamide ball-and-stick.png
Systematic (IUPAC) name
6-ethoxy-1,3-benzothiazole-2-sulfonamide
Clinical data
Legal status  ?
Pharmacokinetic data
Protein binding ~89%
Half-life 2.5-5.5 hours
Identifiers
CAS number 452-35-7 YesY
ATC code None
PubChem CID 3295
DrugBank DB00311
ChemSpider 3179 YesY
UNII Z52H4811WX YesY
KEGG D02441 YesY
ChEBI CHEBI:101096 YesY
ChEMBL CHEMBL18 YesY
Chemical data
Formula C9H10N2O3S2 
Mol. mass 258.319 g/mol
 YesY (what is this?)  (verify)

Ethoxzolamide (alternatively known as Ethoxyzolamide) is a sulfonamide medication that functions as a carbonic anhydrase inhibitor. It is used in the treatment of glaucoma, duodenal ulcers, and as a diuretic. It may also be used in the treatment of some forms of epilepsy.