Ethyl Phosphorochloridite

Title: Ethyl Phosphorochloridite
CAS Registry Number: 589-57-1
CAS Name: Phosphorochloridous acid diethyl ester
Additional Names: diethylchlorophosphinate; diethylchlorophosphonate; diethylphosphorous acid chloride; ethyl chlorophosphite
Molecular Formula: C4H10ClO2P
Molecular Weight: 156.55
Percent Composition: C 30.69%, H 6.44%, Cl 22.65%, O 20.44%, P 19.79%
Line Formula: (C2H5O)2PCl
Literature References: Prepd by passing chlorine into diethylphosphorous acid in ligroin contg Na wire: Arbusow, Arbusow, Ber. 65, 195 (1932); by heating triethyl phosphite and phosphorus trichloride; or by adding phosphorus trichloride to a soln of ethanol and diethylaniline in ether: Cook et al., J. Chem. Soc. 1949, 2021.
Properties: Liquid. Characteristic odor of acid chlorides. Fumes in moist air; reacts violently with water. d420 1.0816; d00 1.0962; d020 1.0747. bp760 153-155°; (also reported as bp760 143-148°); bp30 63-65°; bp15 45-53°; bp10 37-38°. nD20 1.4350.
Boiling point: bp760 153-155°; (also reported as bp760 143-148°); bp30 63-65°; bp15 45-53°; bp10 37-38°
Index of refraction: nD20 1.4350
Density: d420 1.0816; d00 1.0962; d020 1.0747
Use: In peptide synthesis.
Ethyl Propiolate Ethyl Propionate Ethyl p-Toluenesulfonate Ethyl Salicylate Ethyl Silicate