Title: Etidocaine
CAS Registry Number: 36637-18-0
CAS Name: N-(2,6-Dimethylphenyl)-2-(ethylpropylamino)butanamide
Additional Names: 2-(ethylpropylamino)-2¢,6¢-butyroxylidide
Molecular Formula: C17H28N2O
Molecular Weight: 276.42
Percent Composition: C 73.87%, H 10.21%, N 10.13%, O 5.79%
Literature References: Prepn: H. J. F. Adams et al., DE 2162744; eidem, US 3812147 (1972, 1974 both to Astra). Activity and toxicity studies: eidem, J. Pharm. Sci. 61, 1829 (1972).
Derivative Type: Hydrochloride
CAS Registry Number: 36637-19-1
Manufacturers' Codes: W-19053
Trademarks: Duranest (Astra)
Molecular Formula: C17H28N2O.HCl
Molecular Weight: 312.88
Percent Composition: C 65.26%, H 9.34%, N 8.95%, O 5.11%, Cl 11.33%
Properties: Crystals from abs ethanol-ether and isopropanol-isopropylether, mp 203-203.5°. LD50 in female mice (mg/kg): 6.7 i.v.; 99 s.c. (Adams, 1972).
Melting point: mp 203-203.5°
Toxicity data: LD50 in female mice (mg/kg): 6.7 i.v.; 99 s.c. (Adams, 1972)
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).
Etidronic Acid Etifelmin Etifoxine Etilefrin Etiocholane

Systematic (IUPAC) name
Clinical data
Trade names Duranest
AHFS/ Micromedex Detailed Consumer Information
MedlinePlus a603026
Pregnancy cat. B1 (AU) B (US)
Legal status -only (US)
Routes Parenteral
Pharmacokinetic data
Bioavailability n/a
Metabolism Hepatic
Half-life 2.5 hours
Excretion Renal
CAS number 36637-18-0 N
ATC code N01BB07
PubChem CID 37497
IUPHAR ligand 2621
DrugBank n/a
ChemSpider 34400 YesY
KEGG D04095 YesY
Chemical data
Formula C17H28N2O 
Mol. mass 276.42 g/mol
 N (what is this?)  (verify)

Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery.[1]