Etodroxizine

Title: Etodroxizine
CAS Registry Number: 17692-34-1
CAS Name: 2-[2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethoxy]ethanol
Additional Names: 1-(p-chlorobenzhydryl)-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]piperazine; 1-(p-chloro-a-phenylbenzyl)-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]diethylenediamine; hydrochlorbenzethylamine
Molecular Formula: C23H31ClN2O3
Molecular Weight: 418.96
Percent Composition: C 65.94%, H 7.46%, Cl 8.46%, N 6.69%, O 11.46%
Literature References: Prepn: Morren, GB 817231 (1959). GC determn in plasma: R. Pentz, A. Schutt, Arch. Toxicol. 39, 225 (1978). Clinical evaluations in insomnia: R. Loire, A. Perrin, Lyon Med. 219, 1795 (1968); S. Fedeli, Brux. Med. 48, 517 (1968). Toxicology: M. Giurgea, J. Puigdevall, Proc. Eur. Soc. Study Drug Toxic. 9, 134 (1968).
Properties: Liquid, bp0.01 250°.
Boiling point: bp0.01 250°
Derivative Type: Dimaleate
CAS Registry Number: 56335-21-8
Trademarks: Indunox (UCB); Drimyl (Cassenne)
Molecular Formula: C23H31ClN2O3.2C4H4O4
Molecular Weight: 651.10
Percent Composition: C 57.19%, H 6.04%, Cl 5.45%, N 4.30%, O 27.03%
Properties: LD50 orally in rats: 920 mg/kg (Giurgea, Puigdevall).
Toxicity data: LD50 orally in rats: 920 mg/kg (Giurgea, Puigdevall)
Therap-Cat: Hypnotic.
Keywords: Sedative/Hypnotic.
Status: This monograph has been retired and is no longer subject to revision or update.
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