Fenbendazole

Title: Fenbendazole
CAS Registry Number: 43210-67-9
CAS Name: [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Additional Names: 5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester; methyl 5-(phenylthio)-2-benzimidazolecarbamate
Manufacturers' Codes: HOE-881v
Trademarks: Panacur (Intervet)
Molecular Formula: C15H13N3O2S
Molecular Weight: 299.35
Percent Composition: C 60.18%, H 4.38%, N 14.04%, O 10.69%, S 10.71%
Literature References: Prepn: H. Loewe et al., DE 2164690; eidem, US 3954791 (1973, 1976 both to Hoechst); C. Baeder et al., Experientia 30, 753 (1974). Efficacy vs gastrointestinal nematodes in swine: Enigk et al., Dtsch. Tieraerztl. Wochenschr. 81, 177 (1974).
Properties: Light brownish-gray, odorless, tasteless crystalline powder, mp 233° (dec). Insol in water; insol or only very slightly sol in the usual solvents. Freely sol in DMSO.
Melting point: mp 233° (dec)
Therap-Cat-Vet: Anthelmintic (Nematodes).
Fenbenicillin Fenbuconazole Fenbufen Fenbutatin Oxide Fenbutrazate

Fenbendazole
Fenbendazole.svg
Systematic (IUPAC) name
methyl N-(6-phenylsulfanyl-1H-benzoimidazol-
2-yl)carbamate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Identifiers
CAS number 43210-67-9 YesY
ATC code P02CA06 QP52AC13
PubChem CID 3334
ChemSpider 3217 YesY
UNII 621BVT9M36 YesY
KEGG D04140 YesY
ChEBI CHEBI:77092
ChEMBL CHEMBL37161 YesY
Chemical data
Formula C15H13N3O2S 
Mol. mass 299.349 g/mol
 YesY (what is this?)  (verify)

Fenbendazole (Hoechst brand names Panacur and Safe-Guard, Intervet Panacur and Panacur Rabbit) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the taenia species of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles and strongyloides and can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits and seals. Drug interactions may occur if using bromsalan flukicides such as dibromsalan and tribromsalan. Abortions in cattle and death in sheep have been reported after using these medications together.[1]