Fenipentol

Title: Fenipentol
CAS Registry Number: 583-03-9
CAS Name: a-Butylbenzenemethanol
Additional Names: a-butylbenzyl alcohol; phenylbutylcarbinol; 1-phenyl-1-hydroxypentane; phenylpentanol; PC 1; Ph BC
Trademarks: Pancoral (Eisai)
Molecular Formula: C11H16O
Molecular Weight: 164.24
Percent Composition: C 80.44%, H 9.82%, O 9.74%
Literature References: Synthesis: Fourneau, Puyal, An. Soc. Esp. Fis. Quim. 18, 323 (1920); Adams, Vander Werf, J. Am. Chem. Soc. 72, 4368 (1950); Protiva et al., Chem. Listy 46, 37 (1952). Prepn of the drug: Scheffler, Engelhorn, GB 915815; eidem, US 3084100 (both 1963 to Thomae). Pharmacology: Engelhorn, Arzneim.-Forsch. 10, 255 (1960); Beck, Bierwisch, ibid. 20, 693 (1970). Metabolism: Koss et al., ibid. 14, 195 (1964).
Properties: Colorless or slightly yellow liquid. bp12 123-124°. nD20 1.5112. Miscible with organic liquids. Practically insol in water.
Boiling point: bp12 123-124°
Index of refraction: nD20 1.5112
Therap-Cat: Choleretic. Also used in treatment of mild chronic pancreatitis.
Keywords: Choleretic.
Fennel Fenoldopam Fenoprofen Fenoterol Fenoverine