Title: Fenpentadiol
CAS Registry Number: 15687-18-0
CAS Name: 2-(4-Chlorophenyl)-4-methyl-2,4-pentanediol
Additional Names: 2-methyl-4-(p-chlorophenyl)-2,4-pentanediol
Manufacturers' Codes: RD-292
Trademarks: Tredum (Hœatrol)
Molecular Formula: C12H17ClO2
Molecular Weight: 228.72
Percent Composition: C 63.02%, H 7.49%, Cl 15.50%, O 13.99%
Literature References: Prepn: Valette, FR M1984 (1963 to Labs Albert Rolland), C.A. 60, 2828h (1964). Psychopharmacology: J. Ginet et al., Arzneim.-Forsch. 21, 1 (1971). Pharmacokinetics: Y. Dormand, J. C. Levron, Eur. J. Toxicol. 5, 43 (1972). Clinical evaluations: P. Mouren et al., Marseille Med. 106, 555 (1969); P. J. Parquet, Lille Med. 18, 836 (1973). Toxicity: H. Kriegel et al., Arzneim.-Forsch. 21, 9 (1971).
Properties: Crystals from petr ether, mp 76.5°. uv max (0.1% in abs ethanol): 228 nm. LD50 in male, female mice, rats (mg/kg): 940, 995, 1200, 1250 orally (Kriegel).
Melting point: mp 76.5°
Absorption maximum: uv max (0.1% in abs ethanol): 228 nm
Toxicity data: LD50 in male, female mice, rats (mg/kg): 940, 995, 1200, 1250 orally (Kriegel)
Therap-Cat: Antidepressant.
Keywords: Antidepressant.
Status: This monograph has been retired and is no longer subject to revision or update.
Fenpiclonil Fenpiprane Fenpiverinium Bromide Fenpropathrin Fenpropidin

Systematic (IUPAC) name
Clinical data
Legal status Prescription only
Routes Oral
CAS number 15687-18-0
ATC code None
PubChem CID 85896
ChemSpider 77482
UNII BLO7300903 YesY
Chemical data
Formula C12H17ClO2 
Mol. mass 228.72 g/mol

Fenpentadiol (Tredum, Trefenum) is a drug formerly used as an antidepressant in Europe.[1][2] It also has stimulant, sedative, and anxiolytic effects, with the latter two occurring only at higher doses.[3][4]