Title: Fenquizone
CAS Registry Number: 20287-37-0
CAS Name: 7-Chloro-1,2,3,4-tetrahydro-4-oxo-2-phenyl-6-quinazolinesulfonamide
Additional Names: 7-chloro-2-phenyl-6-sulfamyl-1,2,3,4-tetrahydro-4-quinazolinone
Manufacturers' Codes: MG-13054
Molecular Formula: C14H12ClN3O3S
Molecular Weight: 337.78
Percent Composition: C 49.78%, H 3.58%, Cl 10.50%, N 12.44%, O 14.21%, S 9.49%
Literature References: Thiazide-like diuretic with saluretic and hypocalciuric activity. Prepn: M. G. Biressi et al., Farmaco Ed. Sci. 24, 199 (1969). Prepn of potassium salt: M. Carissimi, F. Ravenna, BE 799087 (1973 to Maggioni); eidem, US 3870720 (1975). Gas-liquid chromatography: A. Marzo et al., J. Chromatogr. 272, 95 (1983). Metabolism in dogs: D. Ceriani et al., Farmaco Ed. Sci. 31, 379 (1976). Human pharmacokinetics: G. C. Maggi et al., Arzneim.-Forsch. 35, 994 (1985). Site of action: C. Ferrando et al., J. Pharm. Pharmacol. 33, 219 (1981). Clinical trials: O. Biadi et al., Drugs Exp. Clin. Res. 7, 763 (1981); N. Glorioso et al., Curr. Ther. Res. 35, 483 (1984); A. Cupisti et al., ibid. 38, 293 (1985).
Properties: mp >310°. Insol in water.
Melting point: mp >310°
Derivative Type: Monopotassium salt
CAS Registry Number: 52246-40-9
Trademarks: Idrolone (Maggioni)
Molecular Formula: C14H12ClKN3O3S
Molecular Weight: 376.88
Percent Composition: C 44.62%, H 3.21%, Cl 9.41%, K 10.37%, N 11.15%, O 12.74%, S 8.51%
Properties: White crystalline powder. Sol in water. pH ~9.9 (1% aqueous soln).
Therap-Cat: Diuretic.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.
Fenspiride Fensulfothion Fenthion Fentiazac Fenticlor

Systematic (IUPAC) name
Clinical data
Legal status  ?
ATC code C03BA13
PubChem CID 68548
ChemSpider 61822 YesY
KEGG D04161 YesY
Chemical data
Formula C14H12ClN3O3S 
Mol. mass 337.781 g/mol
 YesY (what is this?)  (verify)

Fenquizone (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics. Fenquizone is used primarily in the treatment of oedema and hypertension. [1]