Title: Fenspiride
CAS Registry Number: 5053-06-5
CAS Name: 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Additional Names: decaspiride; DESP
Molecular Formula: C15H20N2O2
Molecular Weight: 260.33
Percent Composition: C 69.20%, H 7.74%, N 10.76%, O 12.29%
Literature References: a-Adrenergic blocker. Prepn: NL 6504602; Regnier et al., US 3399192 (1965 and 1968, both to Sci. Union et Cie-Soc. Franc. Recherche Méd.). Pharmacology: LeDouarec et al., Arzneim.-Forsch. 19, 1263 (1969); Duhault et al., ibid. 22, 1947 (1972).
Derivative Type: Hydrochloride
CAS Registry Number: 5053-08-7
Manufacturers' Codes: NAT-333; NDR-5998A
Trademarks: Decaspir (Pulitzer); Fluiden (Lafare); Pneumorel (Stroder); Respiride (Schiapparelli); Tegencia (Elmu); Viarespan (Servier)
Molecular Formula: C15H20N2O2.HCl
Molecular Weight: 296.79
Percent Composition: C 60.70%, H 7.13%, N 9.44%, O 10.78%, Cl 11.95%
Properties: Crystals decomp 232-233°. Soluble in water. LD50 i.v. in mice: 106 mg/kg; orally in rats: 437 mg/kg (LeDouarec).
Toxicity data: LD50 i.v. in mice: 106 mg/kg; orally in rats: 437 mg/kg (LeDouarec)
Therap-Cat: Bronchodilator.
Keywords: a-Adrenergic Blocker; Bronchodilator.
Fensulfothion Fenthion Fentiazac Fenticlor Fenticonazole

Fenspiride ball-and-stick animation.gif
Systematic (IUPAC) name
Clinical data
Trade names Eurespal, Pneumorel
AHFS/Drugs.com International Drug Names
Legal status Prescription only
Routes Oral
Pharmacokinetic data
Bioavailability 90%[1]
Half-life 14–16 hours
Excretion Urine (90%), feces (~10%)
CAS number 5053-06-5 YesY
ATC code R03BX01 R03DX03
PubChem CID 68626
KEGG D07949 YesY
Chemical data
Formula C15H20N2O2 
Mol. mass 260.331 g/mol
 N (what is this?)  (verify)

Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.[2] In Russia it is approved for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.[3]