Flopropione

Title: Flopropione
CAS Registry Number: 2295-58-1
CAS Name: 1-(2,4,6-Trihydroxyphenyl)-1-propanone
Additional Names: 2¢,4¢,6,-trihydroxypropiophenone; phloropropiophenone
Manufacturers' Codes: RP-13907
Trademarks: Argobyl (Specia); Cospanon (Eisai); Flopion (Kyoritsu); Gallepronin (Taiyo); Gasstenon (Tatsumi); Labroda (Specia); Labrodax (Specia); Pasmus (Daiichi); Profenon (Morishita); Spamorin (Tanabe Seiyaku); Spasmoril; Supanate (Nippon Shinyaku); Supazlun (Kowa)
Molecular Formula: C9H10O4
Molecular Weight: 182.17
Percent Composition: C 59.34%, H 5.53%, O 35.13%
Literature References: Prepn: Shinoda, J. Pharm. Soc. Jpn. 1927, 111; Canter et al., J. Chem. Soc. 1931, 1245; Howells, Little, J. Am. Chem. Soc. 54, 2451 (1932).
Derivative Type: Monohydrate
Properties: Needles from water. Anhydr compd, mp 175-176°. Sol in ethanol, ether, ethyl acetate, hot water; very slightly sol in cold water.
Melting point: mp 175-176°
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.
Florantyrone Florasulam Floredil Florfenicol Flosequinan

Flopropione
Flopropione.svg
Systematic (IUPAC) name
1-(2,4,6-trihydroxyphenyl)propan-1-one
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Routes Oral
Identifiers
CAS number 2295-58-1
ATC code None
PubChem CID 3362
ChemSpider 3245
UNII 05V5NVB5Y1 YesY
KEGG D01259 YesY
Chemical data
Formula C9H10O4 
Mol. mass 182.17 g/mol
 YesY (what is this?)  (verify)

Flopropione (Compacsul, Cospanon, Ecapron, Pellegal, Argobyl, Floveton, Saritron, Spamorin, Labrodax, Tryalon, Mirulevatin, Padeskin, Profenon) is a spasmolytic or antispasmodic agent.[1] It acts as a 5-HT1A receptor antagonist.[1]

It is synthetized from phloroglucinol.[2]