Fludeoxyglucose F18

Title: Fludeoxyglucose F18
CAS Registry Number: 105851-17-0
CAS Name: 2-Deoxy-2-(fluoro-18F)-a-D-glucopyranose
Additional Names: 2-[18F]fluoro-2-deoxy-D-glucose; 18FDG
Molecular Formula: C6H1118FO5
Literature References: Radioactive glucose analog used clinically to evaluate glucose metabolism by PET. Prepn: T. Ido et al., J. Labelled Compd. Radiopharm. 14, 175 (1978). Review of syntheses: T. J. Tewson, Nucl. Med. Biol. 16, 533-551 (1989). Biodistribution: B. M. Gallagher et al., J. Nucl. Med. 19, 1154 (1978). Cerebral glucose measurement in man: M. Reivich et al., Circ. Res. 44, 127 (1979). Clinical evaluation of metabolic imaging in myocardium: R. J. Gropler et al., J. Nucl. Med. 31, 1749 (1990); in tumors: J. Okada et al., ibid. 33, 325 (1992); N. Y. Tse et al., Ann. Surg. 216, 27 (1992). Reviews of imaging in cerebrovascular disease: K. Herholz, W. D. Heiss, Semin. Neurol. 9, 293-300 (1989); Alzheimer's disease: J. M. Hoffman et al., Eur. Neurol. 29, Suppl. 3, 16-24 (1989); brain tumors: R. E. Coleman et al., J. Nucl. Med. 32, 616-622 (1991); pancreatic cancer: M. Zimny, U. Buell, Ann. Oncol. 10, Suppl. 4, S28-S32 (1999).
Therap-Cat: Diagnostic aid (radioactive imaging agent).
Keywords: Diagnostic Aid (Radioactive Imaging Agent).
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