Title: Flunixin
CAS Registry Number: 38677-85-9
CAS Name: 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid
Additional Names: 2-(2-methyl-3-trifluoromethylanilino)nicotinic acid; 2-(a3,a3,a3-trifluoro-2,3-xylidino)nicotinic acid
Manufacturers' Codes: Sch-14714
Molecular Formula: C14H11F3N2O2
Molecular Weight: 296.24
Percent Composition: C 56.76%, H 3.74%, F 19.24%, N 9.46%, O 10.80%
Literature References: Cyclooxygenase inhibitor. Prepn: M. H. Sherlock, N. Sperber, BE 679271; eidem, US 3337570 (1966, 1967 both to Schering). Prepn of the acid and meglumine salt: M. H. Sherlock, BE 812772; idem, US 3839344 (both 1974 to Schering). Pharmacodynamics in horses: M. M. Hardee, J. N. Moore, Res. Vet. Sci. 40, 152 (1986); and pharmacokinetics: L. R. Soma et al., J. Vet. Pharmacol. Ther. 15, 292 (1992). GC determn in urine: M. Johansson, E. -L. Anlér, J. Chromatogr. 427, 55 (1988). Clinical evaluation in horses: J. W. Houdeshell, P. W. Hennessey, J. Equine Med. Surg. 1, 57 (1977). Experimental use in food-producing animals: M. Kopcha, A. S. Ahl, J. Am. Vet. Med. Assoc. 194, 45 (1989). Comparative toxicological study in horses: C. G. MacAllister et al., ibid. 202, 71 (1993).
Properties: Crystals from acetone/hexane, mp 226-228°. pKa¢ 5.82.
Melting point: mp 226-228°
pKa: pKa¢ 5.82
Derivative Type: Meglumine salt
CAS Registry Number: 42461-84-7
Trademarks: Banamine (Schering-Plough); Binixin (Bayer); Finadyne (Fisons)
Molecular Formula: C14H11F3N2O2.C7H17NO5
Molecular Weight: 491.46
Percent Composition: C 51.32%, H 5.74%, F 11.60%, N 8.55%, O 22.79%
Properties: Colorless cryst from ethanol/ether, mp 135-137°. Crystals from acetonitrile, mp 136-139°. Sol in water.
Melting point: mp 135-137°; mp 136-139°
Therap-Cat-Vet: Anti-inflammatory; analgesic; antipyretic.
Flunoxaprofen Fluoboric Acid Fluocinolone Acetonide Fluocortin Butyl Fluocortolone

Flunixin Structural Formulae V.1.svg
Systematic (IUPAC) name
2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
CAS number 38677-85-9 YesY
ATCvet code QM01AG90
PubChem CID 38081
ChemSpider 34911 N
UNII 356IB1O400 YesY
KEGG D04215 YesY
Chemical data
Formula C14H11F3N2O2 
Mol. mass 296.24 g/mol
 N (what is this?)  (verify)

Flunixin is a non-steroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine salt. In the United States, it is regulated by the U.S. Food and Drug Administration (FDA), and may only be lawfully distributed by order of a licensed veterinarian. There are many trade names for the product, as stated below.