Fluoresone

Title: Fluoresone
CAS Registry Number: 2924-67-6
CAS Name: 1-(Ethylsulfonyl)-4-fluorobenzene
Additional Names: ethyl p-fluorophenyl sulfone; p-fluorophenyl ethyl sulfone
Trademarks: Bripadon; Caducid (Wassermann)
Molecular Formula: C8H9FO2S
Molecular Weight: 188.22
Percent Composition: C 51.05%, H 4.82%, F 10.09%, O 17.00%, S 17.04%
Literature References: Prepn: G. Thuillier et al., Compt. Rend. 248, 2492 (1959); P. Rumpf, G. Thuillier, FR M399; eidem, US 3084101 (1962, 1963 both to Centre Nat. Recher. Scient.); A. A. Mignot, P. Rumpf, Bull. Soc. Chim. Fr. 1968, 435. Pharmacology: J. Thuillier et al., Proc. 3rd Meet Coll. Int. Neuro-Psychopharmacol. 1962, 317-326 (Publ. 1964). Clinical evaluation: H. Akimoto, S. Taen, ibid. 326. Gas chromatography: E. Marozzi et al., Farmaco Ed. Prat. 31, 180 (1976).
Properties: Crystals, mp 41°. LD50 orally in mice: 2.5 g/kg (G. Thuillier); also reported as 850 mg/kg (J. Thuillier); 542 mg/kg (Akimoto, Taen).
Melting point: mp 41°
Toxicity data: LD50 orally in mice: 2.5 g/kg (G. Thuillier); also reported as 850 mg/kg (J. Thuillier); 542 mg/kg (Akimoto, Taen)
Therap-Cat: Anticonvulsant; analgesic; anxiolytic.
Keywords: Analgesic (Non-Narcotic); Anticonvulsant; Anxiolytic.
Fluoridamid Fluorine Dioxide Fluorine Monoxide Fluorine Nitrate Fluorine Perchlorate