Flusilazole

Title: Flusilazole
CAS Registry Number: 85509-19-9
CAS Name: 1-[[Bis(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole
Additional Names: bis(4-fluorophenyl)methyl(1H-1,2,4-triazol-1-ylmethyl)silane; fluzilazol
Manufacturers' Codes: DPX-H6573
Trademarks: Nustar (DuPont); Olymp (DuPont); Punch (DuPont)
Molecular Formula: C16H15F2N3Si
Molecular Weight: 315.39
Percent Composition: C 60.93%, H 4.79%, F 12.05%, N 13.32%, Si 8.91%
Literature References: Sterol-inhibiting, broad spectrum foliar fungicide. Prepn: W. K. Moberg, EP 68813; idem, US 4510136 (1983, 1985 both to Du Pont); W. K. Moberg et al., Pest. Sci. Biotech., Proc. 6th Int. Congr. Pest. Chem., 57 (1987). Field performance, physical properties and toxicity: T. M. Fort, W. K. Moberg, Proc. Br. Crop Prot. Conf. - Pests Dis. 1984, 413. Field trials against apple scab: A. R. Biggs, J. Warner, Can. J. Plant Pathol. 9, 41 (1987); and mildew: A. A. J. Swait et al., Tests Agrochem. Cultiv. 8, 42 (1987).
Properties: Crystalline solid, mp 55°. Soly: >2 g/ml in many organic solvents. LD50 in male, female rats (mg/kg): 1110, 674 orally; in rabbits >2000 dermally (Fort, Moberg).
Melting point: mp 55°
Toxicity data: LD50 in male, female rats (mg/kg): 1110, 674 orally; in rabbits >2000 dermally (Fort, Moberg)
Use: Agricultural fungicide.
Fluspirilene Flutamide Fluthiacet-methyl Fluticasone Propionate Flutolanil

Flusilazole
Flusilazole.png
Identifiers
CAS number 85509-19-9
PubChem 73675
Jmol-3D images Image 1
Properties
Molecular formula C16H15F2N3Si
Density 315.392 g/cm3
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Flusilazole (DPX-H6573) is an organosilicon fungicide invented by DuPont, which is used to control fungal infections on a variety of fruit and vegetable crops.[1][2][3] It is moderately toxic to animals and has been shown to produce birth defects and embryotoxicity at high doses.[4][5]