Flutolanil

Title: Flutolanil
CAS Registry Number: 66332-96-5
CAS Name: N-[3-(1-Methylethoxy)phenyl]-2-(trifluoromethyl)benzamide
Additional Names: o-trifluoromethyl-m¢-isopropoxybenzoic anilide; a,a,a-trifluoro-3¢-isopropoxy-o-toluanilide
Manufacturers' Codes: NNF-136
Trademarks: Prostar (AgrEvo); Moncut (Nihon Nohyaku)
Molecular Formula: C17H16F3NO2
Molecular Weight: 323.31
Percent Composition: C 63.15%, H 4.99%, F 17.63%, N 4.33%, O 9.90%
Literature References: Systemic benzanilide fungicide. Prepn: K. Yabutani et al., DE 2731522; eidem, US 4093743 (both 1978 to Nihon Nohyaku). Properties and biological activity: F. Araki, K. Yabutani, Proc. Br. Crop Prot. Conf. - Pests Dis. 1981, 3; F. Araki, Jpn. Pestic. Inf. 47, 23 (1985). Mode of action: K. Motoba et al., Agric. Biol. Chem. 52, 1445 (1988). Degradation study: M. Uchida et al., J. Pestic. Sci. 8, 529 (1983). Control of rice sheath blight: H. Mochizuki et al., ibid. 12, 29 (1987); of fungal diversity on peanuts: R. E. Baird et al., Phytoprotection 76, 101 (1995).
Properties: Odorless, white, crystalline solid. mp 108° (Araki, Yabutani), also reported as mp 104-105° (Araki, 1985). Stable in acid and alkaline solutions. Soly at 20° (g/l): water 0.0096; chloroform 341; methanol 480; benzene 131; xylene 29. Vapor pressure at 20°: 1.33 ´ 10-5 mm Hg. LD50 in male and female rats, male and female mice (mg/kg): >10,000, >10,000 orally; in male and female rats (mg/kg): >5000 dermally (Araki).
Melting point: mp 108° (Araki, Yabutani); mp 104-105° (Araki, 1985)
Toxicity data: LD50 in male and female rats, male and female mice (mg/kg): >10,000, >10,000 orally; in male and female rats (mg/kg): >5000 dermally (Araki)
Use: Agricultural fungicide.
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