Fructose-1,6-diphosphate

Title: Fructose-1,6-diphosphate
CAS Registry Number: 488-69-7
CAS Name: D-Fructose 1,6-bis(dihydrogen phosphate)
Additional Names: 1,6-D-fructosediphosphoric acid; hexose diphosphate; Harden-Young ester
Molecular Formula: C6H14O12P2
Molecular Weight: 340.12
Percent Composition: C 21.19%, H 4.15%, O 56.45%, P 18.21%
Literature References: Formed from fructose-6-phosphate in the presence of ATP, Mg2+ and the enzyme phosphohexokinase. Prepn from glucose, mannose, fructose, sucrose by the action of yeasts: A. Harden, Alcoholic Fermentation (Longmans, Green & Co., New York, 4th ed., 1932); v. Lebedev, Biochem. Z. 36, 254 (1911); cf DE 292817; DE 293864; DE 301590. Fructose-1,6-diphosphate is reversibly split in the presence of aldolase forming 1-phosphodihydroxyacetone and 3-phosphoglyceraldehyde: Meyerhof et al., Biochem. Z. 286, 301 (1936). Metabolism regulation study: M. E. Kirtley, M. McKay, Mol. Cell. Biochem. 18, 141 (1977).
Derivative Type: Sodium salt monohydrate
Trademarks: Esafosfina (Foscama)
Therap-Cat: Roborant; tonic.
Fructose-6-phosphate Fucosamine Fucosterol Fucoxanthin Fucus

Fructose 1,6-bisphosphate
Beta-D-fructose-1,6-bisphosphate wpmp.png
Identifiers
CAS number 488-69-7 YesY
PubChem 445557
ChemSpider 393165 YesY
MeSH fructose-1,6-diphosphate
ChEBI CHEBI:40595 YesY
ChEMBL CHEMBL1089962 YesY
ATC code C01EB07
Jmol-3D images Image 1
Properties
Molecular formula C6H14O12P2
Molar mass 340.116
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Fructose 1,6-bisphosphate, also known as Harden-Young ester, is fructose sugar phosphorylated on carbons 1 and 6 (i.e., is a fructosephosphate). The β-D-form of this compound is very common in cells. The vast majority of glucose and fructose entering a cell will become converted to fructose 1,6-bisphosphate at some point.