Gefarnate

Title: Gefarnate
CAS Registry Number: 51-77-4
CAS Name: (4E,8E)-5,9,13-Trimethyl-4,8,12-tetradecatrienoic acid (2E)-3,7-dimethyl-2,6-octadienyl ester
Additional Names: geranyl farnesylacetate
Manufacturers' Codes: DA-688
Trademarks: Alsanate (Dainippon); Arsanyl (Taiyo); Dixnalate (Sana); Gefanil (Sumitomo); Gefarnil; Gefarnyl; Gefulcer (Ohta); Osteol (Yamanouchi); Salanil (Sato Yakuhin); Zackal (SS Pharm.)
Molecular Formula: C27H44O2
Molecular Weight: 400.64
Percent Composition: C 80.94%, H 11.07%, O 7.99%
Literature References: Prepn: Cardani et al., J. Med. Chem. 6, 457 (1963); BE 617994 (1962 to Ist. de Angeli). Metabolism: G. Coppi et al., Arzneim.-Forsch. 19, 1519 (1969). Clinical evaluation in duodenal ulcer: C. R. Newman, D. A. Montgomery, Br. J. Clin. Pract. 27, 85 (1973).
Properties: Slightly yellowish liq with weak terpenic smell. bp0.05 165-168°. nD20 1.4900. uv max: 204 nm (E1%1cm 486). Sol in alc, ether, dimethylformamide, acetone, fatty oils. Practically insol in water, formamide, ethylene glycol, propylene glycol, glycerine.
Boiling point: bp0.05 165-168°
Index of refraction: nD20 1.4900
Absorption maximum: uv max: 204 nm (E1%1cm 486)
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative.
Geissoschizoline Geissospermine Gellan Gum Gelsemium Gemcitabine

Gefarnate
Skeletal formula
Space-filling model
Systematic (IUPAC) name
(2E)-3,7-dimethylocta-2,6-dien-1-yl (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Identifiers
CAS number 51-77-4 YesY
ATC code A02BX07
PubChem CID 5282182
ChemSpider 4445377 N
UNII 1ISE2Y6ULA YesY
KEGG D01529 YesY
Chemical data
Formula C27H44O2 
Mol. mass 400.637 g/mol
 N (what is this?)  (verify)

Gefarnate is a drug used for the treatment of gastric ulcers.[1]

It also has been proposed for use in the treatment of dry eye syndrome.[2][3]