Gemeprost

Title: Gemeprost
CAS Registry Number: 64318-79-2
CAS Name: (2E,11a,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oic acid methyl ester
Additional Names: 16,16-dimethyl-trans-D2-PGE1 methyl ester
Manufacturers' Codes: ONO-802
Trademarks: Cergem (Searle); Cervagem(e) (M & B); Preglandin (Ono)
Molecular Formula: C23H38O5
Molecular Weight: 394.54
Percent Composition: C 70.02%, H 9.71%, O 20.28%
Literature References: Analog of prostaglandin E1, q.v. Prepn: M. Hayashi et al., DE 2700021; eidem, US 4052512 (both 1977 to Ono); H. Suga et al., Prostaglandins 15, 907 (1978). Effects on uterine contractility and steroid hormone plasma levels: K. Oshima et al., J. Reprod. Fertil. 55, 353 (1979). Effects on reproductive function: K. Matsumoto et al., Nippon Yakurigaku Zasshi 79, 15 (1982), C.A. 96, 98392 (1982). Use in termination of first trimester pregnancy: O. Reiertsen et al., Prostaglandins Leukotrienes Med. 8, 31 (1982).
Therap-Cat: Abortifacient; oxytocic.
Keywords: Abortifacient/Interceptive; Oxytocic; Prostaglandin/Prostaglandin Analog.
Gemfibrozil Gemifloxacin Gemtuzumab Ozogamicin Genite? Gentamicin

Gemeprost
Gemeprost.svg
Systematic (IUPAC) name
methyl (2E,11α,13E,15R)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status  ?
Routes Pessary
Identifiers
CAS number 64318-79-2
ATC code G02AD03
PubChem CID 5282237
ChemSpider 4445416 YesY
UNII 45KZB1FOLS YesY
KEGG D02073 YesY
Synonyms methyl (E)-7-[(1R,2S,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyl-oct-1-enyl]-5-oxo-cyclopentyl]hept-2-enoate
Chemical data
Formula C23H38O5 
Mol. mass 394.545 g/mol
 YesY (what is this?)  (verify)

Gemeprost (16, 16-dimethyl-trans-delta2 PGE1 methyl ester) is an analogue of prostaglandin E1.