Glucametacin

Title: Glucametacin
CAS Registry Number: 52443-21-7
CAS Name: 2-[[[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-D-glucose
Additional Names: 2-[2-[1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamido]-2-deoxy-D-glucose; glucametacine; glucamethacin; indomethacin glucosamide
Molecular Formula: C25H27ClN2O8
Molecular Weight: 518.94
Percent Composition: C 57.86%, H 5.24%, Cl 6.83%, N 5.40%, O 24.66%
Literature References: Deriv of indomethacin, q.v. Prepn: A. Demetrio et al., DE 2223051 (1973 to SIR Lab. Chem. Biol. SpA), C.A. 80, 83529e (1974). Pharmacological study: E. Paroli et al., Arzneim.-Forsch. 28, 819 (1978). Clinical studies: P. Petera et al., Int. J. Clin. Pharmacol. Biopharm. 15, 581 (1977); L. Capelli et al., Curr. Med. Res. Opin. 7, 227 (1981).
Derivative Type: Monohydrate
Trademarks: Euminex (Lacer); Teorema (Panchemie); Teoremac (Farmades)
Molecular Formula: C25H27ClN2O8.H2O
Molecular Weight: 536.96
Percent Composition: C 55.92%, H 5.44%, Cl 6.60%, N 5.22%, O 26.82%
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.
Glucamine Glucofrangulin Glucoheptonic Acid Gluconic Acid Gluconolactone