Gratiogenin

Title: Gratiogenin
CAS Registry Number: 7067-16-5
CAS Name: (3b,9b,10a,24S)-20,24-Epoxy-3,25-dihydroxy-9-methyl-19-norlanost-5-en-11-one
Molecular Formula: C30H48O4
Molecular Weight: 472.70
Percent Composition: C 76.23%, H 10.24%, O 13.54%
Literature References: Tetracyclic triterpene closely related to the cucurbitacins. Prepd by hydrolysis of gratioside: Retzlaff, Arch. Pharm. 240, 561 (1902). Structural studies: Tschesche, Heesch, Ber. 85, 1067 (1952). Revised structure: Tschesche et al., Ann. 674, 196 (1964).
Properties: Clusters of needles from methanol or ethanol, mp 191-196°. [a]D20 +168° (c = 1.193 in chloroform); [a]D20 +151° (c = 0.863 in methanol). Also reported as mp 202-203°. [a]D25 +175 ± 3° (chloroform), (Tschesche, 1964). Freely sol in methanol, ethanol, chloroform, acetone, pyridine. Practically insol in water, ether, petr ether.
Melting point: mp 191-196°; mp 202-203°
Optical Rotation: [a]D20 +168° (c = 1.193 in chloroform); [a]D20 +151° (c = 0.863 in methanol); [a]D25 +175 ± 3° (chloroform)
Status: This monograph has been retired and is no longer subject to revision or update.
Gratioside Gravitol(e) Grayanotoxins Green Fluorescent Protein Grindelia