Guanoxan

Title: Guanoxan
CAS Registry Number: 2165-19-7
CAS Name: [(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]guanidine
Additional Names: (1,4-benzodioxan-2-ylmethyl)guanidine; 2-guanidinomethyl-1,4-benzodioxan
Molecular Formula: C10H13N3O2
Molecular Weight: 207.23
Percent Composition: C 57.96%, H 6.32%, N 20.28%, O 15.44%
Literature References: Prepn: BE 632701; J. Augstein, S. M. Green, US 3247221 (1963, 1966, both to Pfizer); Monro, Chem. Ind. (London) 1964, 1806; Gardner, GB 996708 (1965 to SKF), C.A. 63, 14877d (1965); Yu, Shen, C.A. 66, 94969k (1967). Prepn and properties of (+) and (-)-forms: Stenlake et al., J. Pharm. Pharmacol. 20 (Suppl), 82 (1968). Pharmacology: Augstein et al., J. Med. Chem. 8, 446 (1965); Cession-Fossion, Arch. Int. Pharmacodyn. Ther. 164, 419 (1966); Vidal-Beretewide et al., Arzneim.-Forsch. 19, 947 (1969). Metabolic studies: Jack et al., J. Pharm. Pharmacol. 23, 2225 (1971); Xenobiotica 2, 35 (1972).
Properties: Crystals, mp 164-165°.
Melting point: mp 164-165°
Derivative Type: Sulfate
CAS Registry Number: 5714-04-5
Trademarks: Envacar (Pfizer)
Molecular Formula: (C10H13N3O2)2.H2SO4
Molecular Weight: 512.54
Percent Composition: C 46.87%, H 5.51%, N 16.40%, O 24.97%, S 6.26%
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Guanidine Derivatives.
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Guanoxan
Guanoxan.png
Systematic (IUPAC) name
2-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)guanidine
Clinical data
Legal status  ?
Identifiers
CAS number 2165-19-7
ATC code C02CC03
PubChem CID 16564
UNII 9V0MRL0R5Y YesY
Chemical data
Formula C10H13N3O2 
Mol. mass 207.23 g/mol
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Guanoxan is a sympatholytic drug.