Kopsine

Title: Kopsine
CAS Registry Number: 559-48-8
CAS Name: 3-Hydroxy-22-oxokopsan-1-carboxylic acid methyl ester
Molecular Formula: C22H24N2O4
Molecular Weight: 380.44
Percent Composition: C 69.46%, H 6.36%, N 7.36%, O 16.82%
Literature References: From Kopsia fructicosa A.D., Apocynaceae: Bhattacharya et al., J. Am. Chem. Soc. 71, 3370 (1949). Structure: Spiteller, Monatsh. Chem. 93, 1220 (1962); Govindachari et al., Helv. Chim. Acta 45, 1146 (1962); 46, 572 (1963); Guggisberg et al., ibid. 52, 76 (1969).
Properties: Crystals from alc, dec 217-218°. [a]D27 -14.3 ± 1° (c = 2 in chloroform). uv max (ethanol): 240, 278, 285-286 nm (log e 4.08, 3.37, 3.35). Sol in chloroform; sparingly sol in methanol, ethanol, ethyl acetate, benzene, ether. Practically insol in petr ether, water.
Optical Rotation: [a]D27 -14.3 ± 1° (c = 2 in chloroform)
Absorption maximum: uv max (ethanol): 240, 278, 285-286 nm (log e 4.08, 3.37, 3.35)
Derivative Type: Methiodide
Molecular Formula: C23H27IN2O4
Molecular Weight: 522.38
Percent Composition: C 52.88%, H 5.21%, I 24.29%, N 5.36%, O 12.25%
Properties: Crystals from methanol, dec 194-196°.
Derivative Type: Oxalate
Molecular Formula: C24H26N2O8
Molecular Weight: 470.47
Percent Composition: C 61.27%, H 5.57%, N 5.95%, O 27.21%
Properties: Prisms from alcohol + acetone, dec 154°. Sol in water.
Kosins Krebiozen Kresoxim-methyl Kurchessine Kurcholessine